Diagnosis code __ not valid for patient gender

REJECTION: Diagnosis code (letter/number will be specified) not valid for patient gender

WHAT HAPPENED: Diagnosis code specified in box 21 is not valid for the patient gender selected in box 3.

RESOLUTION: Verify the patient’s gender and check the ICD-10 code’s gender-specific requirements. If needed, update Box 21 with a diagnosis code valid for the patient’s gender and resubmit the claim.